Review





Similar Products

ccuga 27409  (ATCC)
90
ATCC ccuga 27409
Ccuga 27409, supplied by ATCC, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/ccuga 27409/product/ATCC
Average 90 stars, based on 1 article reviews
ccuga 27409 - by Bioz Stars, 2026-02
90/100 stars
  Buy from Supplier
ikk α antibody  (Novus Biologicals)
90
Novus Biologicals ikk α antibody
Ikk α Antibody, supplied by Novus Biologicals, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/ikk α antibody/product/Novus Biologicals
Average 90 stars, based on 1 article reviews
ikk α antibody - by Bioz Stars, 2026-02
90/100 stars
  Buy from Supplier
anti ccr2 pai 27409  (Cell Signaling Technology Inc)
97
Cell Signaling Technology Inc anti ccr2 pai 27409
FIGURE 2 | QSG inhibited activation of TGF-β1/Smad3 through reducing the recruitment of M1 macrophages in myocardial tissue. (A) IF staining showed that splenectomy reduced the recruitment of M1 macrophages in myocardial tissue; QSG treatment decreased the recruitment of M1 macrophages. (B) Masson and Sirius Red staining showed that QSG inhibited cardiac fibrosis. (C) Western blot showed that QSG down-regulated the expressions of AT1, MCP-1 and <t>CCR2</t> in myocardial tissue compared with that in the model group. (D) Western blot showed that QSG decreased the expressions of TGF-β1, Smad3, collagen III and MMP2 in cardiac tissue. All data were presented as means ± SD from independent experiments performed in triplicate. #P < 0.05, ##P < 0.01, ###P < 0.001 vs the sham group; *P < 0.05, **P < 0.01, ***P < 0.001 vs the model group. N = 3 per group.
Anti Ccr2 Pai 27409, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 97/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/anti ccr2 pai 27409/product/Cell Signaling Technology Inc
Average 97 stars, based on 1 article reviews
anti ccr2 pai 27409 - by Bioz Stars, 2026-02
97/100 stars
  Buy from Supplier
ikk alpha antibody (14a231) - azide free  (Bio-Techne corporation)
90
Bio-Techne corporation ikk alpha antibody (14a231) - azide free
FIGURE 2 | QSG inhibited activation of TGF-β1/Smad3 through reducing the recruitment of M1 macrophages in myocardial tissue. (A) IF staining showed that splenectomy reduced the recruitment of M1 macrophages in myocardial tissue; QSG treatment decreased the recruitment of M1 macrophages. (B) Masson and Sirius Red staining showed that QSG inhibited cardiac fibrosis. (C) Western blot showed that QSG down-regulated the expressions of AT1, MCP-1 and <t>CCR2</t> in myocardial tissue compared with that in the model group. (D) Western blot showed that QSG decreased the expressions of TGF-β1, Smad3, collagen III and MMP2 in cardiac tissue. All data were presented as means ± SD from independent experiments performed in triplicate. #P < 0.05, ##P < 0.01, ###P < 0.001 vs the sham group; *P < 0.05, **P < 0.01, ***P < 0.001 vs the model group. N = 3 per group.
Ikk Alpha Antibody (14a231) Azide Free, supplied by Bio-Techne corporation, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/ikk alpha antibody (14a231) - azide free/product/Bio-Techne corporation
Average 90 stars, based on 1 article reviews
ikk alpha antibody (14a231) - azide free - by Bioz Stars, 2026-02
90/100 stars
  Buy from Supplier
pa1-27409  (Thermo Fisher)
90
Thermo Fisher pa1-27409
FIGURE 2 | QSG inhibited activation of TGF-β1/Smad3 through reducing the recruitment of M1 macrophages in myocardial tissue. (A) IF staining showed that splenectomy reduced the recruitment of M1 macrophages in myocardial tissue; QSG treatment decreased the recruitment of M1 macrophages. (B) Masson and Sirius Red staining showed that QSG inhibited cardiac fibrosis. (C) Western blot showed that QSG down-regulated the expressions of AT1, MCP-1 and <t>CCR2</t> in myocardial tissue compared with that in the model group. (D) Western blot showed that QSG decreased the expressions of TGF-β1, Smad3, collagen III and MMP2 in cardiac tissue. All data were presented as means ± SD from independent experiments performed in triplicate. #P < 0.05, ##P < 0.01, ###P < 0.001 vs the sham group; *P < 0.05, **P < 0.01, ***P < 0.001 vs the model group. N = 3 per group.
Pa1 27409, supplied by Thermo Fisher, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/pa1-27409/product/Thermo Fisher
Average 90 stars, based on 1 article reviews
pa1-27409 - by Bioz Stars, 2026-02
90/100 stars
  Buy from Supplier

Image Search Results


FIGURE 2 | QSG inhibited activation of TGF-β1/Smad3 through reducing the recruitment of M1 macrophages in myocardial tissue. (A) IF staining showed that splenectomy reduced the recruitment of M1 macrophages in myocardial tissue; QSG treatment decreased the recruitment of M1 macrophages. (B) Masson and Sirius Red staining showed that QSG inhibited cardiac fibrosis. (C) Western blot showed that QSG down-regulated the expressions of AT1, MCP-1 and CCR2 in myocardial tissue compared with that in the model group. (D) Western blot showed that QSG decreased the expressions of TGF-β1, Smad3, collagen III and MMP2 in cardiac tissue. All data were presented as means ± SD from independent experiments performed in triplicate. #P < 0.05, ##P < 0.01, ###P < 0.001 vs the sham group; *P < 0.05, **P < 0.01, ***P < 0.001 vs the model group. N = 3 per group.

Journal: Frontiers in pharmacology

Article Title: Qishen Granule Improved Cardiac Remodeling via Balancing M1 and M2 Macrophages.

doi: 10.3389/fphar.2019.01399

Figure Lengend Snippet: FIGURE 2 | QSG inhibited activation of TGF-β1/Smad3 through reducing the recruitment of M1 macrophages in myocardial tissue. (A) IF staining showed that splenectomy reduced the recruitment of M1 macrophages in myocardial tissue; QSG treatment decreased the recruitment of M1 macrophages. (B) Masson and Sirius Red staining showed that QSG inhibited cardiac fibrosis. (C) Western blot showed that QSG down-regulated the expressions of AT1, MCP-1 and CCR2 in myocardial tissue compared with that in the model group. (D) Western blot showed that QSG decreased the expressions of TGF-β1, Smad3, collagen III and MMP2 in cardiac tissue. All data were presented as means ± SD from independent experiments performed in triplicate. #P < 0.05, ##P < 0.01, ###P < 0.001 vs the sham group; *P < 0.05, **P < 0.01, ***P < 0.001 vs the model group. N = 3 per group.

Article Snippet: After electrophoresis at 100 V for 1–1.5 h, proteins were transferred to PVDF membranes at 300 mA for 1–1.5 h. Afterwards, the membrane blocked with 5% skim milk for 1–1.5 h at room temperature, incubated on a shaker, and washed with TBS-T. Western blot analysis was conducted using anti-AT1 (ab18801; Abcam, United States), Frontiers in Pharmacology | www.frontiersin.org November 2019 | Volume 10 | Article 1399 anti-MCP-1 (ab25124, Abcam, United States), anti-CCR2 (PAI-27409), anti-TGF-β1 (3711s, Cell Signaling Technology, Germany), anti-Smad3 (ab28379, Abcam, United States), antiMMP2 (ab86607, Abcam, United States), anti-Col III (ab7778, Abcam, United States), anti-VEGF (ab10972, Abcam, United States), anti-CD31 (ab24590, Abcam, United States) and antiGAPDH (ab8245, Abcam, United States) at 4°C overnight.

Techniques: Activation Assay, Staining, Western Blot

FIGURE 5 | QSG suppresses the release of spleen monocytes and recruitment to heart tissues through the splenic Ang II/AT1-cardiac MCP-1/CCR2 pathway to inhibit MR.

Journal: Frontiers in pharmacology

Article Title: Qishen Granule Improved Cardiac Remodeling via Balancing M1 and M2 Macrophages.

doi: 10.3389/fphar.2019.01399

Figure Lengend Snippet: FIGURE 5 | QSG suppresses the release of spleen monocytes and recruitment to heart tissues through the splenic Ang II/AT1-cardiac MCP-1/CCR2 pathway to inhibit MR.

Article Snippet: After electrophoresis at 100 V for 1–1.5 h, proteins were transferred to PVDF membranes at 300 mA for 1–1.5 h. Afterwards, the membrane blocked with 5% skim milk for 1–1.5 h at room temperature, incubated on a shaker, and washed with TBS-T. Western blot analysis was conducted using anti-AT1 (ab18801; Abcam, United States), Frontiers in Pharmacology | www.frontiersin.org November 2019 | Volume 10 | Article 1399 anti-MCP-1 (ab25124, Abcam, United States), anti-CCR2 (PAI-27409), anti-TGF-β1 (3711s, Cell Signaling Technology, Germany), anti-Smad3 (ab28379, Abcam, United States), antiMMP2 (ab86607, Abcam, United States), anti-Col III (ab7778, Abcam, United States), anti-VEGF (ab10972, Abcam, United States), anti-CD31 (ab24590, Abcam, United States) and antiGAPDH (ab8245, Abcam, United States) at 4°C overnight.

Techniques: